KMID : 1225720240160010009
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Allergy, Asthma & Immunology Research : AAIR 2024 Volume.16 No. 1 p.9 ~ p.21
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The KAAACI Guidelines for Sublingual Immunotherapy
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Min Jin-Young
Jee Hye-Mi Lee Hwa-Young Kang Sung-Yoon Kim Kyung-Hoon Kim Ju-Hee Park Kyung-Hee Park So-Young Sung Myong-Soon Lee Young-Soo Yang Eun-Ae Ryu Gwang-Hui Ha Eun-Kyo Lee Sang-Min Lee Yong-Won Chung Eun-Hee Choi Sun-Hee Koh Young-Il Kim Seon-Tae Nahm Dong-Ho Park Jung-Won Shim Jung-Yeon An Young-Min Han Man-Yong Choi Jeong-Hee Shin Yoo-Seob Han Doo-Hee
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Abstract
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Allergen immunotherapy is regarded as the only disease-modifying treatment option for various allergic conditions, including allergic rhinitis and asthma. Among the routes of administration of allergens, sublingual immunotherapy (SLIT) has gained clinical interest recently, and the prescription of SLIT is increasing among patients with allergies. After 30 years of SLIT use, numerous pieces of evidence supporting its efficacy, safety, and mechanism allows SLIT to be considered as an alternative option to subcutaneous immunotherapy. Based on the progressive development of SLIT, the current guideline from the Korean Academy of Asthma, Allergy, and Clinical Immunology aims to provide an expert opinion by allergy, pediatrics, and otorhinolaryngology specialists with an extensive literature review. This guideline addresses the use of SLIT, including 1) mechanisms of action, 2) appropriate patient selection for SLIT, 3) the currently available SLIT products in Korea, and 4) updated information on its efficacy and safety. This guideline will facilitate a better understanding of practical considerations for SLIT.
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KEYWORD
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Allergen immunotherapy, guideline, sublingual immunotherapy
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