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KMID : 1225720240160010009
Allergy, Asthma & Immunology Research : AAIR
2024 Volume.16 No. 1 p.9 ~ p.21
The KAAACI Guidelines for Sublingual Immunotherapy
Min Jin-Young

Jee Hye-Mi
Lee Hwa-Young
Kang Sung-Yoon
Kim Kyung-Hoon
Kim Ju-Hee
Park Kyung-Hee
Park So-Young
Sung Myong-Soon
Lee Young-Soo
Yang Eun-Ae
Ryu Gwang-Hui
Ha Eun-Kyo
Lee Sang-Min
Lee Yong-Won
Chung Eun-Hee
Choi Sun-Hee
Koh Young-Il
Kim Seon-Tae
Nahm Dong-Ho
Park Jung-Won
Shim Jung-Yeon
An Young-Min
Han Man-Yong
Choi Jeong-Hee
Shin Yoo-Seob
Han Doo-Hee
Abstract
Allergen immunotherapy is regarded as the only disease-modifying treatment option for various allergic conditions, including allergic rhinitis and asthma. Among the routes of administration of allergens, sublingual immunotherapy (SLIT) has gained clinical interest recently, and the prescription of SLIT is increasing among patients with allergies. After 30 years of SLIT use, numerous pieces of evidence supporting its efficacy, safety, and mechanism allows SLIT to be considered as an alternative option to subcutaneous immunotherapy. Based on the progressive development of SLIT, the current guideline from the Korean Academy of Asthma, Allergy, and Clinical Immunology aims to provide an expert opinion by allergy, pediatrics, and otorhinolaryngology specialists with an extensive literature review. This guideline addresses the use of SLIT, including 1) mechanisms of action, 2) appropriate patient selection for SLIT, 3) the currently available SLIT products in Korea, and 4) updated information on its efficacy and safety. This guideline will facilitate a better understanding of practical considerations for SLIT.
KEYWORD
Allergen immunotherapy, guideline, sublingual immunotherapy
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